Monthly Archives:
March 2021

Announcing the Angel Anniversary Fund

Announcing the Angel Anniversary Fund

Published: Mar 24, 2021   |   Author: Michele Keene   |   Category: What's New   |   No Comments

2021 marks 25 years since Gabrielle Rich Aouad passed away from leukemia. In honor of this anniversary, we were inspired to take a look back at the many scientific breakthroughs and notable milestones that have defined the past two and a half decades of our Foundation’s history. Thanks to our generous donors, world class Medical Advisory Board, […]

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Carisma Therapeutics Begins Study of CAR Macrophage Therapy for HER2-Overexpressing Solid Tumors

Carisma Therapeutics Begins Study of CAR Macrophage Therapy for HER2-Overexpressing Solid Tumors

Published: Mar 19, 2021   |   Author: Michele Keene   |   Category: Uncategorized   |   No Comments

Big news from the Charisma Therapeutics team, co-founded by Gabrielle’s Angels grantee Dr. Saar Gill – they’ve just started the FIRST EVER clinical trial for a CAR-engineered macrophage (CAR-M) cell therapy. In preclinical trials, the treatment demonstrated the potential to overcome the challenges that have kept CAR T-cell therapies from benefitting patients with solid tumors. […]

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Study finds cancer cells may evade chemotherapy by going dormant

Study finds cancer cells may evade chemotherapy by going dormant

Published: Mar 15, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of “active hibernation” that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study by scientists at Weill Cornell Medicine (including Dr. Ari Melnick, former Gabrielle’s Angels […]

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CRISPR-edited CAR T Cells Enhance Fight Against Blood Cancers

CRISPR-edited CAR T Cells Enhance Fight Against Blood Cancers

Published: Mar 11, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

Congratulations to Gabrielle’s Angels grantee Dr. Marco Ruella and his colleagues at the Perelman School of Medicine University of Pennsylvania on this impressive breakthrough! Dr. Ruella and his team discovered that knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells’ ability […]

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Yale Study Connects Long COVID with Autoantibodies

Yale Study Connects Long COVID with Autoantibodies

Published: Mar 11, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

Our researchers are not only making an impact in blood cancer research, they’re also making important discoveries in the fight against Covid. Immunologists Akiko Iwasaki, PhD, and Gabrielle’s Angels grantee Aaron Ring, MD, PhD, have identified autoantibodies in patients who have had COVID-19. Autoantibodies are antibodies (proteins produced in response to a pathogen) that mistakenly […]

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Rogue antibodies could be driving severe COVID-19

Rogue antibodies could be driving severe COVID-19

Published: Mar 11, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

More details about the important work that one of our grantees, Dr. Aaron Ring at Yale University, has been contributing to throughout the pandemic. He has been focused on discovering answers to questions like why do some people get so much sicker than others? What is behind the extended, multi-organ illness that lasts for months […]

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Dana-Farber Medical Oncology Chair receives Sjöberg Prize for cancer research

Dana-Farber Medical Oncology Chair receives Sjöberg Prize for cancer research

Published: Mar 11, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

Congratulations to 2011 Gabrielle’s Angels Grantee Dr. Benjamin Ebert for being selected to receive the coveted Sjöberg Prize for cancer research. This $1M prize was awarded for Dr. Ebert’s groundbreaking discovery of the mode of action of lenalidomide in the treatment of hematological disorders. The mission of Gabrielle’s Angel Foundation has always been to support […]

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Penn Medicine Cancer Cell Therapy Pioneer Carl June, MD, Named 2021 Dan David Prize Laureate

Penn Medicine Cancer Cell Therapy Pioneer Carl June, MD, Named 2021 Dan David Prize Laureate

Published: Mar 11, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

Congratulations to Dr. Carl June, member of our Medical Advisory Board, for receiving the prestigious Dan David Prize. The Dan David Prize is endowed by the Dan David Foundation, headquartered at Tel Aviv University, which annually awards three prizes of $1 million each to globally inspiring individuals and organizations, honoring outstanding contributions that expand knowledge […]

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Improving Conventional Wisdom: From CAR-T Therapy to Diversity in STEM, Avery Posey Has Big Ideas

Improving Conventional Wisdom: From CAR-T Therapy to Diversity in STEM, Avery Posey Has Big Ideas

Published: Mar 11, 2021   |   Author: Michele Keene   |   Category: Medical Updates   |   No Comments

A fantastic feature on one of Gabrielle’s Angels one-year grantees, Dr. Avery Posey at UPenn. Dr. Posey focuses on optimizing CAR T-cell treatments while decreasing its toxicity. He’s also dedicated to improving access to careers in STEM for students of color and has recently established a pilot program to bring in six students of color […]

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