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John Radcliffe Hospital, University of Oxford
Unravelling clonal complexity in myelofibrosis stem cells though [sic] application of single cell transcriptomics
Not all blood cancer cells can cause disease relapse following treatment. Understanding the biology relapse-causing "cancer stem cells" is critical, but is akin to "finding a needle in a haystack." This grant will support the development of single-cell genetics to better understand the biology of cancer stem cells in myelofibrosis.